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Licence Information

BlackBerry® Quenchers

BlackBerry® Quencher technology: Covered under US Patent #7,879,986, Berry & Associates, Inc. BlackBerry Quencher,' ‘BBQ 650 CEP,' ‘BBQ 650 CPG' and ‘BBQ 650 NHS Ester' are trademarks of Berry & Associates, Inc., MI. The BBQ dye technology is sold under agreement with Berry & Associates, Inc. Products are sold exclusively for R&D use by the end user. They may not be used for clinical or diagnostic purposes.

dPEG® Reagents

dPEG® products are sold under licence from Quanta Biodesign, Ltd, (Plain City, OH), are sold for laboratory use only and are not intended to be used for any other purposes, including but not limited to, in vitro diagnostic purposes, in foods, drugs, medical devices, cosmetics or commercial use. A separate licensing agreement/supply agreement with Quanta BioDesign, Ltd. is required to use the products in applications beyond laboratory use. Customers are responsible to informing Quanta BioDesign, Ltd when products are being used beyond lab use. dPEG® technology is protected by US Patents #7,888,536 and 8,637,711 and US Patent Pending #2013/0052130. dPEG® is a registered trademark of Quanta BioDesign, Ltd.

2'-Fluoro

A licence may be required from Isis Pharmaceuticals, Inc. to incorporate 2'-fluoro modified nucleosides into oligonucleotides as claimed in US Patent Numbers 5,670,633, 6,005,087, 6,531,584 and foreign equivalents.

PNA

PNA monomers are manufactured and sold pursuant to licence under one or more of US Patents Nos. 5,773,571, 6,133,444, 6,172,226, 6,395,474, 6,414,112, 6,613,873, 6,710,163 and 6,713,602, or corresponding patent claims outside the US. PNA Monomers are sold to be used for internal research use only, and are not to be resold unless by separate licence.

SynBase™

SynBase™ is a trademark of Link Technologies Ltd, Bellshill, Scotland.

UNA

UNA oligonucleotide reagents are protected by patent applications owned by Arcturus Therapeutics, Inc. (www.arcturusrx.com) A license from Arcturus enables Link Technologies Ltd to provide to customers UNA phosphoramidite monomer reagents for use in oligonucleotides for research uses only. The products in their original or any modified form may be used only for the customer's internal research purposes and not for commercial, diagnostic, clinical, therapeutic, or other use, including use in humans. The purchase of products does not include or carry an implied right or license for the buyer to use such products in their original or any modified form for commercial use. Customers may not distribute or provide the products in their original or any modified form to any third party.

Vitamin Products

Use of 5'-Niacin-CE Phosphoramidite, 5'-Niacin-C6-CE Phosphoramidite and bisDMT-Pyridoxine-C6-CE Phosphoramidite (Patent Pending PCT/GB2015/050611) is only permitted for incorporation into oligonucleotides for private purposes, including Research Use Only (RUO) oligonucleotides, i.e. not for commercial applications. Purchase of these products from LINK allows the purchaser the right to sell an oligonucleotide modified with the products, but only for RUO by the end-user. This right only applies to product purchased from Link Technologies or a licenced vendor. For all other uses of these products, in particular commercial applications, licensing programs are available from Link Technologies Ltd. For the avoidance of doubt, a separate licence must be sought for any synthesis and commercial sale of any oligonucleotide modified with the product for any non-RUO purpose, such as, but not limited to, therapeutic and diagnostic applications. Please contact us for further details.

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